Computational Biology and Omics Group
Bioinformatics Institute (BII), A*STAR
The Computational Biology and Omics lab is primarily based at the Bioinformatic Institute, ASTAR, Biopolis, Singapore. The lab specialises in a number of cutting-edge methodologies and analyses to interpret the complex, dynamic and large-scale datasets obtained from time-series transcriptomics, proteomics and metabolomics of living cells. The members of our group come with diverse mathematical, computational and statistical expertise with wide international exposure. Depending on the type of data and cell type, the team develops custom-made computational, mathematical and data analytic tools to investigate and predict an optimal outcome of a desired experiment. For example, for the optimal production of an industrially relevant compound, the models developed can test numerous targets in silico and identify/rank the best targets before actual experiments are performed. To understand disease conditions, the dynamic models can predict target for suppressing immune or cancer response (see Publications). Such systems biology approaches reduce laborious experiments, thereby, saving valuable time and cost for projects.
Upcoming Event(s)
Guest Speaker session with Dr. Joshua Tay, Consultant and Asst Prof, National University Hospital on "Expanding spatial RNA-Seq to large cohorts: Bridging a critical gap", 18 Feb 2025, BII, ASTAR.
Kumar Selvarajoo, invited speaker at Global Conference on Gerophysics, Paradox Singapore, Merchant Court, 5 - 6 March, 2025.
Kumar Selvarajoo, invited speaker at COMPUTATIONAL ONCOLOGY WORKSHOP, IIT Madras, 20 - 21 March, 2025, Chennai, India
Recent Highlights (12 months)
Kumar Selvarajoo, keynote speaker on "Systems Biology and Digital Twin approaches for Health and Food Applications" for Science in the Age of Experience, Institut Pasteur, Paris, France, 29 - 30 October, 2024.
Dr Viduthalai Rasheedkhan Regina, guest speaker CBioOmics Science Camp 16 May 2024.
Kumar Selvarajoo, invited speaker at AI and Big Data in Longevity Research, SGINNOVATE, 07 Mar 2024.